Lauren A. Wise

Childhood adversity has been associated with adverse adult health outcomes. We investigated its association with spontaneous abortion (SAB) risk and the potential buffering effects of social support and integration (SSI). This analysis incl…

Discrimination may increase risk of spontaneous abortion (SAB, pregnancy loss <20 weeks' gestation) through physiological responses and limited access to resources. We examined associations between self-reported experiences of discriminatio…

BACKGROUND: Orgasm can be an important component of sexual wellbeing broadly and specifically in the preconception period, yet epidemiologic research on orgasm is limited. METHODS: We used cross-sectional data from Pregnancy Study Online (…

Racialized economic segregation is a known determinant of health disparities that has been associated with adverse pregnancy outcomes. However, no study has investigated its association with fecundability, the per-cycle probability of conce…

BACKGROUND: Oil and gas development-a highly prevalent industry in North America-is often located near residential communities. This industry produces a complex mixture of pollutants that may impact human health. Despite well-documented ass…

BACKGROUND: Use of chemical hair straighteners ("relaxers") is associated with higher risks of hormonally mediated conditions. We hypothesized users of relaxers would have a higher prevalence of abnormal uterine bleeding (AUB) and dysmenorr…

STUDY QUESTION: To what extent is male physical activity (PA) associated with fecundability (per-cycle probability of conception)? SUMMARY ANSWER: Preconception levels of vigorous, moderate, or total PA were not consistently associated wit…

BACKGROUND: Female sexual function is important for sexual well-being, general health, fertility, and relationship satisfaction. Distressing impairments in sexual function, clinically recognized as female sexual dysfunction (FSD), can manif…

Bola Grace and colleagues argue that using digital health technologies ethically can increase the scope and scale of research and connect systems to improve women’s health

BACKGROUND: Female sexual function is important for positive sexual expression, relationship satisfaction, and overall health and wellbeing. Female sexual dysfunction (FSD), which affects ∼40% of premenopausal women, may manifest as issues …

OBJECTIVE: To assess whether exposure to lower-chlorinated PCBs from building materials is associated with increased incidence of UL, endometriosis, and PCOS in female residents. METHODS: We studied 21,619 residents of two Danish partially…

BACKGROUND: Fertility success among mixed-sex couples often depends on frequency and timing of sexual intercourse, yet little research has evaluated the association between preconception sexual function and time-to-pregnancy. OBJECTIVE: To…

STUDY QUESTION: To what extent are there racial and ethnic disparities in fecundability in North America? SUMMARY ANSWER: In a North American preconception cohort study, we observed large differences in fecundability across racial and ethn…

STUDY QUESTION: To what extent are self-reported diagnoses of food allergies associated with fecundability, the per-cycle probability of conception? SUMMARY ANSWER: Fecundability was not appreciably associated with self-reported food aller…

BACKGROUND: Despite the fact that painful intercourse is common among reproductive-aged females, little research has evaluated how people manage painful intercourse while trying to conceive. AIM: To characterize the self-reported frequency…

INTRODUCTION: Menstrual health is a key patient-reported outcome beyond its importance as a general indicator of health and fertility. However, menstrual function was not measured in the clinical trials of COVID-19 vaccines. The purpose of …

We examined the association between childhood adversity and fecundability (the per-cycle probability of conception), and the extent to which childhood social support modified this association. We used data from 6318 female participants aged…

STUDY QUESTION: To what extent do self-reported sleep duration and non-daytime work schedules in either partner affect the rate of spontaneous abortion (SAB)? SUMMARY ANSWER: Incidence of SAB had little association with female sleep durati…

BACKGROUND: Black women and people with uteri have utilized collectivistic and relational practices to improve health outcomes in the face of medical racism and discrimination for decades. However, there remains a need for interventions to …

BACKGROUND: The use of fertility indicators to predict ovulation has largely been studied for contraceptive purposes, while less so as fertility-promoting tools. OBJECTIVE: To investigate the association between fertility indicators and fe…

Objective: To compare 12-month post-treatment health-related quality of life (HR-QoL) and symptom severity (SS) changes among patients with symptomatic uterine fibroids (SUF) not seeking fertility and undergo a hysterectomy, abdominal myome…

STUDY QUESTION: To what extent is preconception maternal or paternal coronavirus disease 2019 (COVID-19) vaccination associated with miscarriage incidence? SUMMARY ANSWER: COVID-19 vaccination in either partner at any time before conceptio…

ObjectiveTo assess the effect of randomization to FertilityFriend.com, a mobile computing fertility-tracking app, on fecundability.DesignParallel non-blinded randomized controlled trial nested within the Pregnancy Study Online (PRESTO), a N…

RESEARCH QUESTION: Are gravidity, parity and breastfeeding history associated with anti-Müllerian hormone concentration among African-American women of reproductive age? DESIGN: This study included baseline data from the Study of the Envir…

BACKGROUND: Metals may influence reproductive health, but few studies have investigated correlates of metal body burden among reproductive-aged women outside of pregnancy. Furthermore, while there is evidence of racial disparities in exposu…