Trovik J

No ORCID on file · 4 papers in corpus · active 2013-2018

Study types

  • review 1

Condition tags

  • endometriosis 1
review 2018
Genetic overlap between endometriosis and endometrial cancer: evidence from cross‐disease genetic correlation and GWAS meta‐analyses
Cancer medicine ·doi:10.1002/cam4.1445

Abstract Epidemiological, biological, and molecular data suggest links between endometriosis and endometrial cancer, with recent epidemiological studies providing evidence for an association between a previous diagnosis of endometriosis and…

2018
Identification of nine new susceptibility loci for endometrial cancer.
Nature communications ·doi:10.1038/s41467-018-05427-7

Endometrial cancer is the most commonly diagnosed cancer of the female reproductive tract in developed countries. Through genome-wide association studies (GWAS), we have previously identified eight risk loci for endometrial cancer. Here, we…

2015
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
Human molecular genetics ·doi:10.1093/hmg/ddu552

Common variants in the hepatocyte nuclear factor 1 homeobox B (HNF1B) gene are associated with the risk of Type II diabetes and multiple cancers. Evidence to date indicates that cancer risk may be mediated via genetic or epigenetic effects …

2013
Polymorphisms in inflammation pathway genes and endometrial cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology ·doi:10.1158/1055-9965.epi-12-0903

BackgroundExperimental and epidemiologic evidence have suggested that chronic inflammation may play a critical role in endometrial carcinogenesis.MethodsTo investigate this hypothesis, a two-stage study was carried out to evaluate single-nu…