van Marion ES — Endo Lab

2025

Sperm H3K9me3 levels are associated with embryo developmental dynamics and biochemical pregnancy in IVF patients with normozoospermia.

Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-025-01505-w

BackgroundThe posttranslational histone modification H3K9me3 is crucial for constitutive heterochromatin (cHC) and supports genome stability and gene regulation during development. This epigenetic mark persists in human sperm post histone-t…

2022

A higher preconceptional paternal body mass index influences fertilization rate and preimplantation embryo development.

Andrology ·doi:10.1111/andr.13128

BackgroundObesity is a worldwide problem affecting the health of millions of people throughout the life course. Studies reveal that obesity impairs sperm parameters and epigenetics, potentially influencing embryonic development.ObjectiveTo …

2021

Higher preconceptional maternal body mass index is associated with faster early preimplantation embryonic development: the Rotterdam periconception cohort.

Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00822-0

BackgroundOverweight and obesity affect millions of people globally, which has also serious implications for reproduction. For example, treatment outcomes after in vitro fertilisation (IVF) are worse in women with a high body mass index (BM…

2020

Preconceptional Maternal Vegetable Intake and Paternal Smoking Are Associated with Pre-implantation Embryo Quality.

Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00220-8

Inadequate nutrition and lifestyle behaviors, particularly during the periconception period, are associated with a negative impact on embryonic and subsequent fetal development. We investigated the associations between parental nutritional …