Some observational studies have suggested an association between pelvic inflammatory disease (PID) and ovarian cancer (OC), but the causality between PID and OC remains unclear. To investigate the causal association between PID and 7 OCs, w…
Background: Endometriosis is a complex, multifactorial disease characterized by the growth of endometrial-derived cells outside the uterus. Abnormal proliferation of ectopic lesions and chronic inflammation contribute to the onset and progr…
OBJECTIVE: To investigate the association of triglyceride-glucose index (TyG) and uric acid to high-density lipoprotein cholesterol ratio (UHR) with the prevalence of uterine fibroids (UF), and to evaluate the dose-response relationship and…
Early rescue intracytoplasmic sperm injection (Re-ICSI) can prevent total fertilization failure (TFF) during conventional in vitro fertilization (IVF). However, the implantation rate of Re-ICSI embryos is lower than that of direct ICSI duri…
Effective health interventions are a priority for future infertility research, and effective interventions in patient-centered care are still needed. A multi-center prospective study was conducted in order to investigate the effects of a ph…
OBJECTIVES: The aim of our study was to explore the role of circular RNA_0061140 (circ_0061140) in adenomyosis progression and its associated mechanism. DESIGN: We first analyzed the expression pattern of circ_0061140 in endometrial tissue…
Long noncoding RNAs are a group of more than 200 nt, nonprotein coding RNAs, some of which are dysregulated in many pathophysiological processes including endometriosis. This study aims to clarify the roles of dysregulated growth arrest-spe…
BACKGROUND: The management of adenomyosis is challenging and limiting. Qiu's Neiyi recipe (Qiu) is a traditional Chinese medicine (TCM) prescription clinically used for endometriosis treatment in China, but the effect and mechanism of Qiu o…
The present study aimed to investigate the role of miR-30c in endometriosis (EMs) and the underlying mechanism. The expression of miR-30c and plasminogen activator inhibitor type 1 (PAI-1) mRNA in EMs tissues was detected by reverse transcr…
OBJECTIVE: To analyze the potential association between the single nucleotide polymorphisms (SNP) of the vascular endothelial growth factor (VEGF) gene with the risk of endometriosis by meta-analysis. METHODS: Published case-control studie…