He-Feng Huang

OBJECTIVE: To investigate the possible roles of cyclin B1 and cyclin-dependent kanase1 cyclin-dependent kanase1 play in the pathogenesis and development of endometriosis and their association with the ovarian hormones. METHODS: Twenty-nine…

OBJECTIVE: To investigate the expression of aquaporin 1 (AQP1) in endometrium of patients with menorrhagia. METHODS: RT-PCR and immunohistochemistry were carried out in twenty women with normal menstrual cycle to confirm the expression of …

OBJECTIVE: To investigate c-fos and matrix metalloproteinase-9 (MMP-9) expression in the endometrium from women with or without endometriosis throughout the menstrual cycle, and to explore the correlation of c-fos expression with MMP-9 expr…

OBJECTIVE: To investigate the role of nitric oxide (NO) in the pathogenesis of early endometriosis-associated infertility. METHODS: The volume of peritoneal fluids was recorded and the concentration of NO in peritoneal fluid and serum was …

Endometriosis is a common disease of reproductive age women and infertility is one of its clinical manifestations. Infertility of patients with severe endometriosis may be attributed to the anatomy alteration of pelvis.However, the infertil…

OBJECTIVE: To establish a mouse model for endometriosis and to evaluate roles of vascular endothelial growth factor (VEGF) and matrix metalloproteinase-2 (MMP-2) in the formation of disease. DESIGN: Experimental laboratory study. SETTING:…

OBJECTIVE: To determine matrix metalloproteinase 2 (MMP-2) levels in sera and peritoneal fluids of women with or without endometriosis-associated infertility and to determine whether MMP-2 had correlation with 17beta-E(2) and P in the sera …