Heng Liu

ORCID: 0000-0003-3923-7526 · 4 papers in corpus
lab-animal 2025
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2500112122

Gonadotropin-releasing hormone receptor (GnRHR) is critical for reproductive health and a key therapeutic target for endocrine disorders and hormone-responsive cancers. Using high-resolution cryoelectron microscopy, we determined the struct…

lab-animal 2023
Cancer cell ·doi:10.1016/j.ccell.2023.03.002

ARID1A, encoding a subunit of the SWI/SNF complex, is mutated in ∼50% of clear cell ovarian carcinoma (OCCC) cases. Here we show that inhibition of the mevalonate pathway synergizes with immune checkpoint blockade (ICB) by driving inflammas…

other 2022
Medicine ·doi:10.1097/md.0000000000032433

BACKGROUND: Regardless of unique status or symptoms, any woman with endometriosis is at risk of developing mental health issues such as anxiety and depression. Cognitive behavioral therapy (CBT) is an effective psychological treatment for d…

case-report 2009
BMJ case reports ·doi:10.1136/bcr.10.2008.1063

Psammocarcinoma is a rare form of serous carcinoma of the ovary or peritoneum, and it is characterised by extensive psammoma body formation and invasion of surrounding structures. This report describes the case of a 42-year-old woman who pr…