Yu Cao

ORCID: 0009-0000-5027-9298 · 3 papers in corpus
article 2026
A multi-dimensional computational screening strategy for rapid identification of active components from traditional chinese medicine: Validation and application in Liangdi decoction against endometriosis
Computational biology and chemistry ·doi:10.1016/j.compbiolchem.2026.109118

AIMS: This study aims to develop and validate a Multi-Dimensional Computational Screening (MDCS) strategy to identify bioactive components by jointly considering target affinity, exposure potential, and safety, using Liangdi decoction (LDD)…

article 2022
Safety, pharmacokinetics, and pharmacodynamics of SHR7280, an oral gonadotropin-releasing hormone antagonist in healthy premenopausal women
Frontiers in pharmacology ·doi:10.3389/fphar.2022.1027648

Background: Treatment with gonadotropin-releasing hormone (GnRH) antagonists is a powerful strategy to suppress gonadotropin activity in women with sex hormone-dependent disorders. Herein, we provide the safety, pharmacokinetics (PK), and p…

article 2020
Association between mitochondrial DNA D-loop region polymorphisms and endometriosis in a Chinese population
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-020-01853-z

ObjectiveTo investigate the correlation between endometriosis and mitochondrial DNA (mtDNA) D-loop single nucleotide polymorphisms (SNPs) and haplotype, as well as the predictive power of certain SNPs in reproductive outcomes in a Chinese H…