Anna Maria D’Alessandro

2023

Acyl-Carnitines Exert Positive Effects on Mitochondrial Activity under Oxidative Stress in Mouse Oocytes: A Potential Mechanism Underlying Carnitine Efficacy on PCOS.

Biomedicines ·doi:10.3390/biomedicines11092474

Carnitines play a key physiological role in oocyte metabolism and redox homeostasis. In clinical and animal studies, carnitine administration alleviated metabolic and reproductive dysfunction associated with polycystic ovarian syndrome (PCO…

article 2023

P-375 Effect of D-Chiro-Inositol in a mouse model of endometriosis

·doi:10.1093/humrep/dead093.732

Abstract Study question Can D-Chiro Inositol administration mitigate the phenotype of endometriosis in a mouse model? Summary answer Based on an endometriosis mouse model, we demonstrated that administration of D-Chiro Inositol can reduce d…

2015

Sirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and Aging.

Oxidative medicine and cellular longevity ·doi:10.1155/2015/659687

In search for strategies aimed at preventing oxidative threat to female fertility, a possible role of sirtuins has emerged. Sirtuins (silent information regulator 2 (Sir2) proteins), NAD(+) dependent enzymes with deacetylase and/or mono-ADP…