Rosalind Walley

ORCID: 0000-0002-4990-2377 · 2 papers in corpus
review 2011
The translational challenge in the development of new and effective therapies for endometriosis: a review of confidence from published preclinical efficacy studies
Human Reproduction Update ·doi:10.1093/humupd/dmr030

BACKGROUND: Endometriosis is a benign gynaecological condition that presents symptoms of chronic pelvic pain and the ectopic growth of endometrial lesions at sites on the peritoneum. Few new approaches to the management of the disease sympt…

article 2011
The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
The Journal of pharmacology and experimental therapeutics ·doi:10.1124/jpet.111.183848

There is considerable ongoing investment in the research and development of selective progesterone receptor (PR) modulators for the treatment of gynecological conditions such as endometriosis. Here, we provide the first report on the clinic…