Xin Lv

ORCID: 0000-0002-5431-4529 · 3 papers in corpus
lab-animal 2024
Genistein inhibits HIF-1α and attenuates high glucose-induced peritoneal mesothelial-mesenchymal transition and fibrosis via the mTOR/OGT pathway
Scientific reports ·doi:10.1038/s41598-024-74879-3

Peritoneal fibrosis has been linked to hypoxia-inducible factor 1-alpha (HIF-1α) as well as O-linked-N-acetylglucosaminylation (O-GlcNAcylation) in peritoneal dialysis (PD). Genistein, recognized for its HIF-1α inhibitory and antifibrotic e…

lab-animal 2024
NADPH oxidase 4-mediating oxidative stress contributes to endometriosis
Journal of applied genetics ·doi:10.1007/s13353-023-00810-7

NADPH oxidase 4 (NOX4) plays an important role in the regulation of oxidative stress, which is associated with endometriosis. This study aims to investigate the effects of NOX4 in endometriosis and its molecular mechanisms. Clinical specime…

review 2023
Immunotherapy: A promising novel endometriosis therapy
Frontiers in immunology ·doi:10.3389/fimmu.2023.1128301

Endometriosis is a common disease of the female reproductive system and has malignant features. Although endometriosis by itself is a benign disease, its erosive growth characteristics lead to severe pelvic pain and female infertility. Unfo…