Hodson L

ORCID: 0000-0002-2648-6526 · 1 paper in corpus

2022

Obesity Due to Steroid Receptor Coactivator-1 Deficiency Is Associated With Endocrine and Metabolic Abnormalities.

The Journal of clinical endocrinology and metabolism ·doi:10.1210/clinem/dgac067

ContextGenetic variants affecting the nuclear hormone receptor coactivator steroid receptor coactivator, SRC-1, have been identified in people with severe obesity and impair melanocortin signaling in cells and mice. As a result, obese patie…