Dalli J

ORCID: 0000-0001-6328-3640 · 3 papers in corpus
2022
MCTR3 reprograms arthritic monocytes to upregulate Arginase-1 and exert pro-resolving and tissue-protective functions in experimental arthritis.
EBioMedicine ·doi:10.1016/j.ebiom.2022.103974

BackgroundRheumatoid arthritis (RA) is a progressive degenerative disorder that leads to joint destruction. Available treatments only target the inflammatory component with minimal impact on joint repair. We recently uncovered a previously …

2015
Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome.
Biochimica et biophysica acta ·doi:10.1016/j.bbalip.2014.08.006

Acute inflammatory responses are protective, yet without timely resolution can lead to chronic inflammation and organ fibrosis. A systems approach to investigate self-limited (self-resolving) inflammatory exudates in mice and structural elu…

2015
The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution.
Seminars in immunology ·doi:10.1016/j.smim.2015.03.004

Studies into the mechanisms in resolution of self-limited inflammation and acute reperfusion injury have uncovered a new genus of pro-resolving lipid mediators coined specialized pro-resolving mediators (SPM) including lipoxins, resolvins, …