Huo Q

No ORCID on file · 3 papers in corpus · active 2018-2021
2021
Free CA125 promotes ovarian cancer cell migration and tumor metastasis by binding Mesothelin to reduce DKK1 expression and activate the SGK3/FOXO3 pathway.
International journal of biological sciences ·doi:10.7150/ijbs.52097

Objective: CA125/MUC16 is an O-glycosylated protein that is expressed on the surfaces of ovarian epithelial cells. This molecule is a widely used tumor-associated marker for diagnosis of ovarian cancer. Recently, CA125 was shown to be invol…

2021
The function of LncRNA-H19 in cardiac hypertrophy.
Cell & bioscience ·doi:10.1186/s13578-021-00668-4

Cardiac hypertrophy, characterized by the enlargement of cardiomyocytes, is initially an adaptive response to physiological and pathological stimuli. Decompensated cardiac hypertrophy is related to fibrosis, inflammatory cytokine, maladapti…

2018
The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese.
Aging ·doi:10.18632/aging.101461

Copy number variations (CNVs) have been shown to cause numerous diseases, however, their roles in human lifespan remain elusive. In this study, we investigate the association of CNVs with longevity by comparing the Han Chinese genomes of lo…