Isabelle Richard

No ORCID on file · 1 paper in corpus · active 2023
2023
An integrin-targeting AAV developed using a novel computational rational design methodology presents improved targeting of the skeletal muscle and reduced liver tropism
·doi:10.21203/rs.3.rs-3466229/v1

Abstract Current adeno-associated virus (AAV) gene therapy using nature-derived AAVs is limited by non-optimal tissue targeting. In the treatment of muscular diseases (MD), high doses are therefore often required, but can lead to severe ad…