Pauliina Kronqvist

ORCID: 0000-0001-8922-0648 · 1 paper in corpus

article 2022

Overexpression of Human Estrogen Biosynthetic Enzyme Hydroxysteroid (17beta) Dehydrogenase Type 1 Induces Adenomyosis-like Phenotype in Transgenic Mice

International journal of molecular sciences ·doi:10.3390/ijms23094815

Hydroxysteroid (17beta) dehydrogenase type 1 (HSD17B1) is an enzyme that converts estrone to estradiol, while adenomyosis is an estrogen-dependent disease with poorly understood pathophysiology. In the present study, we show that mice unive…