Jing Jin

目的 基于网络药理学并运用分子对接和动物实验进行验证，平冲降逆方治疗子宫内膜异作症（EMs）的潜在分子机制。 方法 借助TCMSP和BATMAN-TCM 数据库检索平冲降逆方活性成分和作用靶点，并构建“中药-活性成分-靶点”网络。以“endometriosis”为关键词在 Genecards、OMIM和TTD数据库获取疾病靶点。将交集靶点导入 STRING 数据库和 Cytoscape 软件筛选核心治疗靶点，借助 DAVID 数据库进行GO富集分析和KEGG富集分析。利…

BACKGROUND: Endometriosis (EMs) is a pathological condition characterized by the ectopic growth of endometrial tissue outside the uterine cavity. This study aimed to investigate the role of FOXQ1 in the pathogenesis of EMs, particularly thr…

ABSTRACT In recent years, reticulocyte-binding protein homologue 5 (RH5) has emerged as a leading blood-stage Plasmodium falciparum malaria vaccine antigen. The most advanced blood-stage vaccine candidate in a Phase 2b clinical trial, RH5…

BACKGROUND: Thin endometrium (TE) is a common cause of female infertility in clinical practice. Platelet-rich Plasma (PRP) therapy becomes a novel treatment for thin endometrium; however, its clinical application remains controversial. This…

ETHNOPHARMACOLOGICAL RELEVANCE: Pingchong Jiangni recipe (PJR) is often used in the treatment of endometriosis (EM). This formula has been clinically validated by the State Administration of Traditional Chinese Medicine Key Specialties Coll…

Luteal phase deficiency (LPD) is a significant contributor to infertility and miscarriage. Bushen Zhuyun Prescription (BSZY) is a traditional Chinese medicine formula that has potential to treat LPD. To investigate the effect of BSZY in tre…

OBJECTIVE: (1) To characterize the cytokine expression profiles of endometriosis related infertile women in comparison to fertile women with endometriosis; (2) to investigate the correlation of the cytokine levels from different tissues. M…