Top journals
Frequent coauthors
- Wang C 2
- Nie H 2
- Liao L 2
- Ronny Drapkin 2
- Wu S 2
- Zhou W 2
- Aaron R. Goldman 2
- Liu H 2
- Gottlieb E 1
- Ernst Lengyel 1
2025
Subunits of the SWI/SNF chromatin remodeling complex are altered in ∼20% of human cancers. Exemplifying the alterations is the ARID1A mutation that occurs in ∼50% of ovarian clear-cell carcinoma (OCCC), a disease with limited therapeutic op…
2023
ARID1A, encoding a subunit of the SWI/SNF complex, is mutated in ∼50% of clear cell ovarian carcinoma (OCCC) cases. Here we show that inhibition of the mevalonate pathway synergizes with immune checkpoint blockade (ICB) by driving inflammas…