Keke Zhang

No ORCID on file · 6 papers in corpus
other 2026
Reactive oxygen species signaling promotes lesion development in endometriosis through activation of the CHK1/SGK1 pathway
Science bulletin ·doi:10.1016/j.scib.2025.10.038
article 2026
Zinc Finger Protein 143 Promotes Endometriotic Lesion Growth and Fibrosis through the Plasminogen Activator Inhibitor-1 Pathway
The American journal of pathology ·doi:10.1016/j.ajpath.2026.06.002

Endometriosis is a chronic, estrogen-dependent gynecologic disorder characterized by the ectopic growth of endometrial tissue outside the uterus. Zinc finger protein 143 (ZNF143) is a DNA-binding transcription factor, yet its role in endome…

article 2025
Clinical efficacy and safety of Chinese patent medicines combined with hormonal therapy for endometriosis after laparoscopic surgery: A Bayesian network meta-analysis
Complementary therapies in clinical practice ·doi:10.1016/j.ctcp.2025.102020

BACKGROUND AND PURPOSE: Chinese patent medicines (CPMs), standardized herbal formulations widely used in clinical practice, combined with hormones have shown favorable therapeutic effects in the adjuvant treatment of endometriosis (EMS) aft…

article 2024
Paris polyphylla ethanol extract and polyphyllin I ameliorate adenomyosis by inhibiting epithelial-mesenchymal transition
Phytomedicine : international journal of phytotherapy and phytopharmacology ·doi:10.1016/j.phymed.2024.155461

BACKGROUND: The active ingredients of the Chinese medical herb Paris polyphylla, P. polyphylla ethanol extract (PPE) and polyphyllin I (PPI), potentially inhibit epithelial-mesenchymal transition (EMT) in tumors. However, the roles of these…

article 2022
Mechanism Study of Cinnamomi Ramulus and Paris polyphylla Sm. Drug Pair in the Treatment of Adenomyosis by Network Pharmacology and Experimental Validation
Evidence-based complementary and alternative medicine : eCAM ·doi:10.1155/2022/2624434

OBJECTIVE: To explore the molecular mechanism of the Cinnamomi ramulus and Paris polyphylla Sm. (C-P) drug pair in the treatment of adenomyosis (AM) based on network pharmacology and animal experiments. METHODS: Via a network pharmacology …

preprint 2022
Trans-Cinnamaldehyde inhibition of cytoskeleton-induced invasion and migration by regulating the Rho/ROCK pathway in adenomyosis
·doi:10.22541/au.165519364.49734412/v1

Some of the key steps in adenomyosis (AM) are the migration and invasion of adenomyosis derived cells (AMDC); these processes require rearrangement of the cytoskeleton which Rho/ROCK signaling pathway is involved. The aim of the current stu…