Lim CL

ORCID: 0000-0002-2926-892X · 3 papers in corpus
2026
Ligand-Dependent and -Independent Functions of Activation Function 1 of Progesterone Receptor in Genome-Wide Gene Regulation and in Cell Proliferation and Apoptosis of Breast Cancer Cells.
International journal of molecular sciences ·doi:10.3390/ijms27062916

Progesterone receptor (PR) regulates gene expression through recruiting coregulators and general transcription factors by activation functions AF1 and AF2. AF1 localizes to the non-conserved and disordered N-terminal domain and is believed …

2022
Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus.
BMC biology ·doi:10.1186/s12915-022-01410-3

BackgroundProgesterone receptor (PGR) is a master regulator of uterine function through antagonistic and synergistic interplays with oestrogen receptors. PGR action is primarily mediated by activation functions AF1 and AF2, but their physio…

2022
Phytochemicals and Nano-Phytopharmaceuticals Use in Skin, Urogenital and Locomotor Disorders: Are We There?
Plants (Basel, Switzerland) ·doi:10.3390/plants11091265

Nanomedicines emerged from nanotechnology and have been introduced to bring advancements in treating multiple diseases. Nano-phytomedicines are synthesized from active phytoconstituents or plant extracts. Advancements in nanotechnology also…