Crabtree GR

ORCID: 0000-0002-6639-8707 · 2 papers in corpus
2016
Cold Spring Harbor perspectives in medicine ·doi:10.1101/cshperspect.a026930

During the last decade, a host of epigenetic mechanisms were found to contribute to cancer and other human diseases. Several genomic studies have revealed that ∼20% of malignancies have alterations of the subunits of polymorphic BRG-/BRM-as…

2015
Science advances ·doi:10.1126/sciadv.1500447

Over the past 4 years, nearly 100 exome sequencing studies have revealed the high frequency of mutations in the genes encoding the subunits of ATP-dependent chromatin remodelers in human cancer. Most of these mutations are within the genes …