Sevcan Aydın

ORCID: 0009-0009-7765-6124 · 4 papers in corpus
article 2026
Screening of a Novel Synonymous DNAH5 Variant in Histopathologically Confirmed Adenomyosis Cases from Turkiye
Biomedicines ·doi:10.3390/biomedicines14071435

Background/Objectives: Adenomyosis is a common estrogen-dependent gynecological condition with a largely undefined genetic architecture. Ciliary dysfunction has been implicated in its pathogenesis, positioning genes governing ciliary struct…

article 2026
Unveiling a Genetic Link Between Adenomyosis and Carcinogenesis via Whole-Exome Sequencing: Could NTN1-Mediated Epithelial Mesenchymal Transition Be a Shared Mechanism?
·doi:10.26650/experimed.1877834

Objective: Adenomyosis is a benign uterine condition characterized by the invasion of endometrial glands and stromal tissue into the myometrium. It exhibits cancer-like characteristics, such as epithelial-mesenchymal transition (EMT). We ai…

other 2025
Exome-Based Identification of Candidate Genes in Sporadic Adenomyosis Cases
Diagnostics ·doi:10.3390/diagnostics15233069

Background: Adenomyosis is a benign uterine disorder defined by the invagination of ectopic endometrial-like tissue into the myometrium, causing heavy menstrual bleeding and pain. While its pathogenesis remains unclear, shared-symptomology …

article 2023
Whole exome sequencing reveals novel candidate variants for endometriosis utilizing multiple affected members in a single family
Molecular genetics & genomic medicine ·doi:10.1002/mgg3.2312

BACKGROUND: Endometriosis is an estrogen-dependent, chronic inflammatory disease that affects 10% of women during the reproductive ages. Despite the estimated 50% heritability for the condition, only 26% was associated with common genetic v…