Sushma S Thomas

No ORCID on file · 2 papers in corpus

meta-analysis 2019

Discovery of common and rare genetic risk variants for colorectal cancer

Nature genetics ·doi:10.1038/s41588-018-0286-6

To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence variants and Haplotype Reference Consortium panel variants into genome…

observational 2011

Associations between polymorphisms in glucuronidation and sulfation enzymes and sex steroid concentrations in premenopausal women in the United States

The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2010.12.014

Glucuronidation, catalyzed by UDP-glucuronosyltransferases (UGT) and sulfation, catalyzed by sulfotransferases (SULT), are pathways through which sex steroids are metabolized to less active compounds. These enzymes are highly polymorphic an…