Heintz OK

No ORCID on file · 3 papers in corpus · active 2023-2025

Study types

  • preprint 2
  • other 1

Condition tags

  • endometriosis 3
other 2025
Pro-endometriosis macrophage release of IL-33 is key for endometriosis pain and lesion formation
bioRxiv : the preprint server for biology ·doi:10.1101/2025.10.20.683510

Endometriosis is a painful gynecological inflammatory disease affecting up to 10% of females. When released by sensory neurons, calcitonin gene-related peptide (CGRP) shapes immunity, a process known as neuroimmune communication. We previou…

preprint 2023
Nociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth
·doi:10.1101/2023.08.28.555101

Abstract Endometriosis is a debilitating and painful gynecological inflammatory disease affecting approximately 15% of women. Current treatments are ineffective for a significant fraction of patients, underscoring the need for new medical t…

preprint 2023
Targeting NGF but not VEGF or BDNF signaling reduces endometriosis-associated pain in mice
·doi:10.1101/2023.12.05.570181

Abstract Introduction Endometriosis is a chronic inflammatory disease that affects ∼10% of women. A significant fraction of patients experience limited or no efficacy with current therapies. Tissue adjacent to endometriosis lesions often ex…