Mary D. Sammel

Study objectiveTo determine the impact of surgical wait time on healthcare use and surgical outcomes for patients undergoing hysterectomy for benign gynecologic indications.DesignRetrospective cohort study.SettingUrban, academic tertiary ca…

ObjectiveTo estimate the incidence and identify risk factors for atypical endometrial hyperplasia (AH) and endometrial cancer (EC) in American women undergoing infertility evaluation.DesignCase-control study.SettingAcademic reproductive end…

OBJECTIVE: To assess the impact of endometriosis, alone or in combination with other infertility diagnoses, on IVF outcomes. DESIGN: Population-based retrospective cohort study of cycles from the Society for Assisted Reproductive Technolog…

BackgroundAlthough follicle stimulating hormone (FSH) is known to be predictive of age at final menstrual period (FMP), previous methods use FSH levels measured at time points that are defined relative to the age at FMP, and hence are not u…

BackgroundAlthough close observation of serum estradiol (E2) levels remains a mainstay of assessing clinical response to controlled ovarian stimulation, the prognostic value of any change in E2 levels after administration of hCG remains unc…

ContextAnti-mullerian hormone (AMH) has emerged as a marker of ovarian reserve and a possible surrogate measure of reproductive aging.ObjectiveThe aim of the study was to evaluate the predictive value of AMH levels in determining the median…

ObjectiveTo determine the exact nature and timing of alterations in thyroid function throughout controlled ovarian hyperstimulation (COH).DesignProspective cohort study.SettingUniversity fertility clinic.Patient(s)Fifty-seven women undergoi…

ObjectiveTo evaluate the performance of a novel biomarker, a disintegrin and metalloprotease-12 (ADAM-12), to differentiate an ectopic pregnancy (EP) from normal intrauterine pregnancies (IUPs).DesignCase-control study.SettingThree urban ac…

ObjectiveTo estimate response of diagnosis and symptom-based subtypes to sertraline treatment.MethodsThis was a secondary data analysis for women who were diagnosed with premenstrual syndrome (PMS) or premenstrual dysphoric disorder and tre…

ObjectiveTo identify core symptoms that discriminate premenstrual syndrome (PMS) in prospective daily diary ratings and determine the association of these symptoms with functional impairment.MethodsThe study analyzed prospective daily sympt…

OBJECTIVE: To identify potential novel biomarkers that differ between subjects with and without endometriosis and that might aid in developing a noninvasive, serum-based diagnostic test. DESIGN: Case-control evaluation of a diagnostic test…

Based on a recent review of the medical literature, a clinical diagnosis of infertility may not agree with strict criteria. Standardized definitions of diagnostic categories are essential for accurate patient prognosis and future research.

ContextThe duration of treatment after achieving a satisfactory response is unknown in the treatment of premenstrual syndrome. This information is needed in view of the improvement provided by medication vs the adverse effects and costs of …

OBJECTIVE: To evaluate whether a combination of putative markers of inflammation and CA-125 could serve as a multiple-marker screening test for endometriosis in a heterogeneous population of patients. DESIGN: Case-control evaluation of a d…

Because imaging methods are unreliable for diagnosing or staging endometriosis, a definitive diagnosis requires surgery. The fact that the disease produces a local, and probably also a systemic, inflammatory process raises the possibility t…