Lei Jia

ORCID: 0000-0002-4876-7417 · 4 papers in corpus
rct 2026
Autologous bone marrow mesenchymal stem cell mitochondrial transplantation in recurrent assisted reproductive technology failure: a randomized controlled trial
Stem cell research & therapy ·doi:10.1186/s13287-026-05059-5

BACKGROUND: Mitochondrial dysfunction contributes to poor embryo quality and recurrent assisted reproductive technology (ART) failure. Mitochondrial transplantation (MIT), which involves supplementing oocytes with exogenous mitochondria, ha…

other 2024
Mood disorders influencing endometriosis and adenomyosis: Mendelian randomisation study
BJPsych open ·doi:10.1192/bjo.2024.46

BACKGROUND: Many studies have found an association between mood-disorder-related traits and endometriosis and adenomyosis. However, the cause-effect relationship remains unclear. AIMS: We conducted Mendelian randomisation analyses to evalu…

lab-animal 2021
Single-cell transcriptome and cell-specific network analysis reveal the reparative effect of neurotrophin-4 in preantral follicles grown in vitro
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00818-w

BACKGROUND: In-vitro-grow (IVG) of preantral follicles is essential for female fertility preservation, while practical approach for improvement is far from being explored. Studies have indicated that neurotrophin-4 (NT-4) is preferentially …

lab-animal 2020
Transferrin and antioxidants partly prevented mouse oocyte oxidative damage induced by exposure of cumulus-oocyte complexes to endometrioma fluid
Journal of ovarian research ·doi:10.1186/s13048-020-00738-0

BACKGROUND: Exposure of oocytes to the endometrioma fluid has an adverse effect on embryonic quality. To determine whether adding transferrin and antioxidants to culture medium could counteract detrimental effects on mouse cumulus-oocyte co…