Hui Shen

ORCID: 0000-0001-9767-4084 · 13 papers in corpus
lab-animal 2026
Cancer research ·doi:10.1158/0008-5472.can-25-1527

UNLABELLED: Mitigating DNA damage in the fallopian tube epithelium (FTE) is essential for preventing tubo-ovarian high-grade serous carcinoma (HGSC). In this study, we demonstrated that the stimulator of interferon genes (STING) is abundant…

2026
·doi:10.1158/0008-5472.32675390

Quantification of IHC staining for STING conducted on a tumor microarray including cores from healthy FT, FT from patients with gynecological inflammation resulting from endometriosis or chronic salpingitis, and Stage I/Stage II HGSC

other 2025
Nature communications ·doi:10.1038/s41467-025-58145-2

The human Fallopian tube (FT) is an important organ in the female reproductive system and has been implicated as a site of origin for pelvic serous cancers, including high-grade serous tubo-ovarian carcinoma (HGSC). We have generated compre…

2024
·doi:10.1158/0008-5472.c.7002665

AbstractClear cell ovarian carcinoma (CCOC) and endometrioid ovarian carcinoma (ENOC) are ovarian carcinoma histotypes, which are both thought to arise from ectopic endometrial (or endometrial-like) cells through an endometriosis intermedia…

2024
·doi:10.1158/0008-5472.c.7002665.v1

AbstractClear cell ovarian carcinoma (CCOC) and endometrioid ovarian carcinoma (ENOC) are ovarian carcinoma histotypes, which are both thought to arise from ectopic endometrial (or endometrial-like) cells through an endometriosis intermedia…

2024
·doi:10.1158/0008-5472.24924089.v1

Figures S1-S5

2024
·doi:10.1158/0008-5472.24924089

Figures S1-S5

2024
·doi:10.1158/0008-5472.24924086.v1

Supplementary Tables S1-10

2024
·doi:10.1158/0008-5472.24924086

Supplementary Tables S1-10

lab-animal 2023
Cancer research ·doi:10.1158/0008-5472.can-23-1362

UNLABELLED: Clear cell ovarian carcinoma (CCOC) and endometrioid ovarian carcinoma (ENOC) are ovarian carcinoma histotypes, which are both thought to arise from ectopic endometrial (or endometrial-like) cells through an endometriosis interm…

lab-animal 2023
Frontiers in endocrinology ·doi:10.3389/fendo.2023.1285667

INTRODUCTION: The number of primordial follicles (PFs) in mammals determines the ovarian reserve, and impairment of primordial follicle formation (PFF) will cause premature ovarian insufficiency (POI). METHODS: By analyzing public single-c…

lab-animal 2019
Nature communications ·doi:10.1038/s41467-019-11403-6

ARID1A and PI3-Kinase (PI3K) pathway alterations are common in neoplasms originating from the uterine endometrium. Here we show that monoallelic loss of ARID1A in the mouse endometrial epithelium is sufficient for vaginal bleeding when comb…

other 2013
Nature communications ·doi:10.1038/ncomms2629

HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this gene differentially associates with epithelial ovaria…