Ferguson B

No ORCID on file · 4 papers in corpus · active 2019-2025
2025
Cervicovaginal microbiome alters transcriptomic and chromatin accessibility signatures across cervicovaginal epithelial barriers.
Microbiome ·doi:10.1186/s40168-025-02223-6

BackgroundThe cervicovaginal microbiome plays a critical role in women's health with microbial communities dominated by Lactobacillus species considered optimal. In contrast, the depletion of lactobacilli and the presence of a diverse array…

2024
Extracellular vesicles from vaginal Gardnerella vaginalis and Mobiluncus mulieris contain distinct proteomic cargo and induce inflammatory pathways.
NPJ biofilms and microbiomes ·doi:10.1038/s41522-024-00502-y

Colonization of the vaginal space with bacteria such as Gardnerella vaginalis and Mobiluncus mulieris is associated with increased risk for STIs, bacterial vaginosis, and preterm birth, while Lactobacillus crispatus is associated with optim…

2023
Nonhuman primate genetic models for the study of rare diseases.
Orphanet journal of rare diseases ·doi:10.1186/s13023-023-02619-3

Pre-clinical research and development relies heavily upon translationally valid models of disease. A major difficulty in understanding the biology of, and developing treatments for, rare disease is the lack of animal models. It is important…

2019
mGAP: the macaque genotype and phenotype resource, a framework for accessing and interpreting macaque variant data, and identifying new models of human disease.
BMC genomics ·doi:10.1186/s12864-019-5559-7

BackgroundNon-human primates (NHPs), particularly macaques, serve as critical and highly relevant pre-clinical models of human disease. The similarity in human and macaque natural disease susceptibility, along with parallel genetic risk all…