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PURPOSE: To evaluate changes in immunoexpression of proteins involved in epigenetic regulation in the uterus in female ICR mice following neonatal exposure to tamoxifen. METHODS: Thirty-two neonatal mice were randomly assigned to 2 groups:…
Abstract STUDY QUESTION Do women’s expectations influence their experiences, perceptions and acceptability of medical treatments for endometriosis and adenomyosis? SUMMARY ANSWER Expectation–experience discordance appears to influence exper…
Abstract Background Endometriosis encompasses heterogeneous lesions, primarily peritoneal and ovarian subtypes, with distinct immunological and fibrotic features. The subtype-specific roles of the immune microenvironment in pathogenesis rem…
Abstract Background Endometriosis encompasses heterogeneous lesions, primarily peritoneal and ovarian subtypes, with distinct immunological and fibrotic features. The subtype-specific roles of the immune microenvironment in pathogenesis rem…
BACKGROUND: Endometriosis encompasses heterogeneous lesions, primarily peritoneal and ovarian subtypes, with distinct immunological and fibrotic features. The subtype-specific roles of the immune microenvironment in pathogenesis remain uncl…
BACKGROUND: This study investigates the clinical characteristics, treatment strategies, and prognosis of ovarian leiomyoma, with the goal of enhancing diagnostic accuracy and therapeutic outcomes for this rare condition. METHODS: We retrosp…
Abstract Endometriosis (EM) is a prevalent gynecological disorder characterized by diagnostic difficulty and high recurrence rates. In this study, single-cell RNA sequencing (scRNA-seq) was performed to characterize endometrial stromal cell…
Isothermal, enzyme-free amplification techniques, such as the hybridization chain reaction (HCR) and catalytic hairpin assembly (CHA), have gained significant attention for mRNA analysis. Despite their potential, these methods still face ch…
OBJECTIVE: To investigate the correlation between endometriosis (EMs) severity and placenta accreta spectrum (PAS) risk in the subsequent pregnancy. METHOD: Clinical records of 2,142 patients who underwent laparoscopic surgery for EMs at F…
BACKGROUND: Adenomyosis is a common gynecological disease and a major contributor to dysmenorrhea that substantially reduces the quality of life of the affected. Dienogest has emerged as a promising drug for treating adenomyosis. A few syst…
PURPOSE: Endometriosis has been hypothesized to increase the risk of preeclampsia (PE) and eclampsia, although the exact mechanism of this relationship is not clear. This study aimed to further explore the potential association between endo…