Ahn YH

ORCID: 0000-0002-1084-0367 · 1 paper in corpus · active 2022
2022
Inhibition of STAT6 Activation by AS1517499 Inhibits Expression and Activity of PPARγ in Macrophages to Resolve Acute Inflammation in Mice.
Biomolecules ·doi:10.3390/biom12030447

Signal transducer and activator of transcription 6 (STAT6) promotes an anti-inflammatory process by inducing the development of M2 macrophages. We investigated whether modulating STAT6 activity in macrophages using AS1517499, the specific S…