Metabolic determinants of oocyte quality and embryonic development remain incompletely understood. Here, we profiled metabolites in human cumulus cells (CCs) and follicular fluid (FF), validated in two mouse models, and integrated transcrip…
BACKGROUND: The objective of this study was to assess the trade-off between cycle continuation and cancellation in slow ovarian response (SOR) patients, and to evaluate the impact of SOR on embryo developmental potential and clinical pregna…
In order to investigate the metabolic characteristics of human follicular fluid (FF) and to reveal potential metabolic predictors of follicular development (FD) with clinical implications, we analyzed a total of 452 samples based on a two-s…
BACKGROUND: To investigate the metabolic profiles in the follicular fluid (FF) samples from patients undergoing in vitro fertilization (IVF) and to analyze the correlations with follicular development. METHODS: The FF samples were obtained…