Bortolotti D

ORCID: 0000-0003-4496-9561 · 5 papers in corpus · active 2015-2020

Condition tags

  • infertility 2
2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00102-8

We recently reported that human herpesvirus 6 (HHV-6) infection is frequently present in endometrial tissue of women with unexplained infertility, and that virus infection induces a profound remodulation of miRNA expression in human cells o…

2020
Frontiers in pharmacology ·doi:10.3389/fphar.2020.00096

The P2X7 receptor (P2X7R) is an ATP-gated ion channel known for its proinflammatory activity. Despite its participation in host defense against pathogens, the role played in viral infections, notably those caused by herpes viruses, has been…

2017
Frontiers in microbiology ·doi:10.3389/fmicb.2017.02525

Background: We have recently reported the presence of Human herpesvirus-6A (HHV-6A) DNA in the 43% of endometrial epithelial cells from primary idiopathic infertile women, with no positivity in fertile women. To investigate the possible eff…

2016
PloS one ·doi:10.1371/journal.pone.0158304

To elucidate the roles of human herpesvirus (HHV)-6 primary unexplained infertile women, a prospective randomized study was conducted on a cohort of primary unexplained infertile women and a cohort of control women, with at least one succes…

2015
International journal of molecular sciences ·doi:10.3390/ijms16035510

The aim of this research was to determine the levels of human leukocyte antigen G (HLA-G) and endometrial Natural Killer ((e)NK) cell percentages in uterine flushing samples from primary and secondary infertile women. sHLA-G levels were low…