Gonzalez XV

ORCID: 0000-0002-1898-5202 · 3 papers in corpus
2026
NMN supplementation as a strategy to improve oocyte quality: a systematic review and transcriptomic analysis.
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-025-03720-1

PurposeOocyte quality declines with age and metabolic stress, largely due to mitochondrial dysfunction and NAD⁺ depletion. Nicotinamide mononucleotide (NMN), a precursor of NAD⁺, has emerged as a potential intervention to restore cellular e…

2023
Integrating imaging-based classification and transcriptomics for quality assessment of human oocytes according to their reproductive efficiency.
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-023-02911-y

PurposeUtilising non-invasive imaging parameters to assess human oocyte fertilisation, development and implantation; and their influence on transcriptomic profiles.MethodsA ranking tool was designed using imaging data from 957 metaphase II …

2023
Systematic review of mRNA expression in human oocytes: understanding the molecular mechanisms underlying oocyte competence.
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-023-02906-9

The biggest cell in the human body, the oocyte, encloses almost the complete machinery to start life. Despite all the research performed to date, defining oocyte quality is still a major goal of reproductive science. It is the consensus tha…