Xiaomeng Wang

ORCID: 0000-0002-4516-4389 · 2 papers in corpus

other 2026

Data pharmacovigilance analysis of medroxyprogesterone-related adverse events in the FDA adverse event reporting system

Expert opinion on drug safety ·doi:10.1080/14740338.2024.2446414

OBJECTIVES: Medroxyprogesterone acetate (MPA), a steroid progesterone, is widely used to treat endometriosis, menstrual disorders, and uterine bleeding in clinical practice. However, the safety profile of MPA requires comprehensive evaluati…

2023

Safety Evaluation of N-((3S,4S)-4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl-1H-pyrazol-5-yl) benzamide (Hu7691) by a Repeated Dose 14-Day Oral Exposure Toxicity Study in Rats

·doi:10.20944/preprints202309.1537.v1

Hu7691 represents a novel Pan-Akt kinase inhibitor, demonstrating excellent selectivity towards non-AGC kinase families and pronounced inhibitory effects on the proliferation of multiple tumor cell lines. However, there is currently a notab…