Amy Brown

ORCID: 0000-0002-6833-6235 · 2 papers in corpus

article 2011

The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human

The Journal of pharmacology and experimental therapeutics ·doi:10.1124/jpet.111.183848

There is considerable ongoing investment in the research and development of selective progesterone receptor (PR) modulators for the treatment of gynecological conditions such as endometriosis. Here, we provide the first report on the clinic…

article 2003

Effect of long-term treatment with low-dose mifepristone on the endometrium

·doi:10.1093/humrep/deg022

BACKGROUND: Mifepristone in low daily doses has contraceptive potential by inhibiting ovulation and menstruation. Because follicular development is maintained, the endometrium is exposed to estrogen for prolonged periods unopposed by proges…