Kim EJ

BackgroundDual anti-CTLA-4/PD-1 inhibitors show efficacy in numerous malignancies. We are the first to report on the efficacy of ipilimumab-nivolumab immunotherapy in a dedicated cohort of patients with gynecologic clear cell carcinomas (CC…

ObjectiveWe aimed to introduce the clinical experience with a new surgical technique, single-port access laparoscopic fundusectomy, and a more efficient uterus-sparing surgical method for treating multiple fibroids in patients without a pre…

With a significant increase in the age-standardized prevalence of infertile men and women, infertility has become a widespread global issue. Furthermore, infertility has led to increased stigma and disease burden. The causes of infertility …

AimsSuppression of the hypothalamic-pituitary-gonadal axis has been widely utilized for the management of gonadal-hormone-dependent diseases such as endometriosis. Efforts to develop orally available gonadotropin-releasing hormone (GnRH) an…

The balanced turnover of collagen is necessary to maintain the mechanical strength of pelvic supportive connective tissues. Homeobox (HOX) A11 is a key transcriptional factor that controls collagen metabolism and homoeostasis in the uterosa…

We investigated a series of uracil analogues by introducing various substituents on the phenyl ring of the N-3 aminoethyl side chain and evaluated their antagonistic activity against human gonadotropin-releasing hormone (GnRH) receptors. An…