Hiroyuki Kagechika

ORCID: 0000-0002-6747-1013 · 2 papers in corpus

other 2018

Novel Nonsteroidal Progesterone Receptor (PR) Antagonists with a Phenanthridinone Skeleton

ACS medicinal chemistry letters ·doi:10.1021/acsmedchemlett.8b00058

The progesterone receptor (PR) plays an important role in various physiological systems, including female reproduction and the central nervous system, and PR antagonists are thought to be effective not only as contraceptive agents and abort…

article 2016

Development of N-(4-Phenoxyphenyl)benzenesulfonamide Derivatives as Novel Nonsteroidal Progesterone Receptor Antagonists

ACS medicinal chemistry letters ·doi:10.1021/acsmedchemlett.6b00184

We report here development of N-(4-phenoxyphenyl)benzenesulfonamide derivatives as a novel class of nonsteroidal progesterone receptor (PR) antagonists. PR plays key roles in various physiological systems, including the female reproductive …