Makrigiorgos GM

ORCID: 0000-0001-7598-2406 · 1 paper in corpus

2021

ESR1 NAPA Assay: Development and Analytical Validation of a Highly Sensitive and Specific Blood-Based Assay for the Detection of ESR1 Mutations in Liquid Biopsies.

Cancers ·doi:10.3390/cancers13030556

A considerable number of estrogen receptor-positive breast cancer (ER+ BrCa) patients develop resistance to endocrine treatment. One of the most important resistance mechanisms is the presence of ESR1 mutations. We developed and analyticall…