Colón-Caraballo M

No ORCID on file · 4 papers in corpus · active 2015-2018

Study types

  • article 3
  • other 1

Condition tags

  • endometriosis 4
article 2018
Effects of histone methyltransferase inhibition in endometriosis†
Biology of reproduction ·doi:10.1093/biolre/ioy030

Although the histone methyltransferase EZH2 and its product H3K27me3 are well studied in cancer, little is known about their role and potential as therapeutic targets in endometriosis. We have previously reported that endometriotic lesions …

article 2018
Human Endometriosis Tissue Microarray Reveals Site-specific Expression of Estrogen Receptors, Progesterone Receptor, and Ki67
Applied immunohistochemistry & molecular morphology : AIMM ·doi:10.1097/pai.0000000000000663

Most available therapies for endometriosis are hormone-based and generally broadly used without taking into consideration the ovarian hormone receptor expression status. This contrasts strikingly with the standard of care for other hormone-…

article 2017
Pharmacological blockage of the CXCR4-CXCL12 axis in endometriosis leads to contrasting effects in proliferation, migration, and invasion†
Biology of reproduction ·doi:10.1093/biolre/iox152

High levels of inflammatory factors including chemokines have been reported in peritoneal fluid and blood of women with endometriosis. CXCL12 mediates its action by interaction with its specific receptor, CXCR4, reported to be elevated in h…

other 2015
H3K27me3 is an Epigenetic Mark of Relevance in Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115578924

Epigenetic mechanisms may play an important role in the etiology of endometriosis. The modification of histones by methylation of lysine residues has been shown to regulate gene expression by changing chromatin structure. We have previously…