Liao, Zhouzhou

Endometriosis, a chronic immune-mediated inflammatory disease, remains elusive in its pathogenesis. Given vitamin D (VD)’s pivotal role in modulating innate and adaptive immune responses, we sought to elucidate how VD modulates inflammatory…

Endometriosis, a chronic immune-mediated inflammatory disease, remains elusive in its pathogenesis. Given vitamin D (VD)’s pivotal role in modulating innate and adaptive immune responses, we sought to elucidate how VD modulates inflammatory…

Additional file 1: Supplementary figure 1. Detection of the mature DCs percentage. At 24 hours after the last rhIL-37 administration, the percentages of CD40-, CD80-, CD86-, and MHC II-positive DCs in serum were determined using flow cytome…

Additional file 1: Supplementary figure 1. Detection of the mature DCs percentage. At 24 hours after the last rhIL-37 administration, the percentages of CD40-, CD80-, CD86-, and MHC II-positive DCs in serum were determined using flow cytome…

Additional file 2: Supplementary figure 2. Analysis of the CD4+T cells. Flow cytometry was used to isolate CD4+T cells from the peripheral blood of healthy mice. N = 3.

Additional file 2: Supplementary figure 2. Analysis of the CD4+T cells. Flow cytometry was used to isolate CD4+T cells from the peripheral blood of healthy mice. N = 3.

Additional file 3: Supplementary figure 3. Analysis of the DCs cells. Flow cytometry was used to isolate DCs from the peripheral blood of healthy mice and endometriosis mouse model. N = 3.

Additional file 3: Supplementary figure 3. Analysis of the DCs cells. Flow cytometry was used to isolate DCs from the peripheral blood of healthy mice and endometriosis mouse model. N = 3.

Additional file 4: Supplementary figure 4. Detection of the iDCs and mDCs percentages. The control-DCs and EMs-DCs were separated, and were then treated with rhIL-37. The percentages of iDCs, mDCs were determined using flow cytometry. N = 3…

Additional file 4: Supplementary figure 4. Detection of the iDCs and mDCs percentages. The control-DCs and EMs-DCs were separated, and were then treated with rhIL-37. The percentages of iDCs, mDCs were determined using flow cytometry. N = 3…

Additional file 5: Supplementary figure 5. Analysis of the maturation of DCs. DCs and EMs-DCs were separated, and were then treated with rhIL-37, and then the percentages of CD40-, CD80-, CD86-, and MHC II-positive DCs were determined using…

Additional file 5: Supplementary figure 5. Analysis of the maturation of DCs. DCs and EMs-DCs were separated, and were then treated with rhIL-37, and then the percentages of CD40-, CD80-, CD86-, and MHC II-positive DCs were determined using…

Additional file 6: Supplementary figure 6. Analysis of the maturation of DCs. The percentages of CD40-, CD80-, CD86-, and MHC II-positive DCs were determined using flow cytometry. N = 3.

Additional file 6: Supplementary figure 6. Analysis of the maturation of DCs. The percentages of CD40-, CD80-, CD86-, and MHC II-positive DCs were determined using flow cytometry. N = 3.

Additional file 7: Supplementary Fig. 7. The drug administration, sampling, and sacrifice process to the mice.

Additional file 7: Supplementary Fig. 7. The drug administration, sampling, and sacrifice process to the mice.

Abstract Background Endometriosis is a serious reproductive and general health consequences. Recombinant human IL-37 (rhIL-37) is an inhibitor of inflammation. Methods ELISA assay was performed to detect the concentration of cytokines. Flow…

Abstract Background Endometriosis is a serious reproductive and general health consequences. Recombinant human IL-37 (rhIL-37) is an inhibitor of inflammation. Methods ELISA assay was performed to detect the concentration of cytokines. Flow…