Zhao J

Levonorgestrel-releasing intrauterine system (LNG-IUS) expulsion rates are markedly elevated (15-37.5%) in patients with adenomyosis compared to those with normal uteri (3-10%), significantly compromising treatment efficacy and adherence. E…

Jin Zhao,* Jianliang Chen,* Xiaoe Wang,* Huabin Wang* Department of Obstetrics and Gynecology, the First People’s Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang,…

BACKGROUND: Angiomyofibroblastoma (AMFB) is a relatively rare benign mesenchymal tumor predominantly observed in premenopausal women. We present a case of vulvar AMFB in a 29-year-old woman, with the tumor measuring approximately 6 cm in di…

BACKGROUND: Endometrial organoids, with their three-dimensional structure and robust hormonal responsiveness, have emerged as valuable models for investigating uterine physiology and embryo implantation. However, conventional derivation fro…

Homocysteine (Hcy) is involved in reproductive metabolism, but the associations of Hcy levels in different reproductive microenvironments with embryo development and pregnancy outcomes remain unclear. This study investigated these associati…

It has been proved that lipids have an effect on endometriosis, and the plasma atherosclerosis index (AIP), as a new lipid index, has not been proved to be correlative to endometriosis. The National Health and Nutrition Examination Survey f…

OBJECTIVE: Polycystic ovary syndrome (PCOS) is a leading cause of female infertility, and early pregnancy outcomes in affected women are affected by multiple interactive factors; however, no well-established predictive tools are available. …

BACKGROUND: Systemic lupus erythematosus (SLE) is a clinically heterogeneous autoimmune disease with multifactorial pathogenesis. Although polygenic risk scores (PRSs) have been developed to enable early prediction, their accuracy remains l…

BACKGROUND: The relationship between endometrial thickness and adverse pregnancy outcomes has garnered significant attention from researchers. The aim of this study was to investigates whether endometrial thickness (EMT) is a risk factor fo…

OBJECTIVES: To evaluate the status and methodological quality of randomized controlled trials published in 2024 on Chinese patent medicines and Classic Traditional Chinese Medicine Prescriptions, providing evidence for clinical practice and…

Oocyte/embryo defects can result in oocyte maturation arrest, fertilization failure, embryonic arrest, and infertility as well as recurrent in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) failures. However, the genet…

BACKGROUND: Non-neoplastic gynecological diseases substantially impact women of childbearing age (WCBA), contributing to global burden. Despite growing awareness, disparities in healthcare access remain widespread across regions and socioec…

BACKGROUND: Hepatocellular carcinoma (HCC) is a malignant tumor originating from hepatocytes, characterized by high mortality rates. Follistatin (FST), an inhibitor of follicle-stimulating hormone, correlates with poor prognosis in some can…

BACKGROUND: In vitro maturation (IVM) presents a potential alternative to conventional IVF for special subgroups of infertile couples. Anti-Müllerian Hormone (AMH) is widely regarded as the most robust biomarker for assessing ovarian reserv…

Gynecological diseases represent a persistent global health burden. According to a WHO report, the global incidence of gynecological diseases exceeds 65%. Furthermore, over 90% of women suffer from gynecological issues to varying degrees. T…

BACKGROUND: Cervical squamous cell carcinoma (CSCC) exhibits profound spatial heterogeneity in evolutionary trajectories across distinct tumour foci, yet the underlying mechanisms remain poorly understood. METHODS: In this study, we perfor…

ETHNOPHARMACOLOGICAL RELEVANCE: Endometriosis (EMs) is a prevalent and challenging gynecological disease and current therapeutic outcomes are suboptimal. Traditional Chinese medicine (TCM) has numerous advantages in treating EMs. Bushen Wen…

BACKGROUND: Elevated homocysteine (HCY) and hyperandrogenism are key metabolic disturbances in polycystic ovary syndrome (PCOS), but their relationship across different reproductive outcomes remains unclear. OBJECTIVE: To investigate outco…

Peritoneal strumosis, also termed highly differentiated follicular carcinoma of ovarian origin (HDFCO), is a rare entity arising from struma ovarii, with extra-ovarian dissemination of thyroid tissue. Radiologic descriptions remain limited.…

BACKGROUND: Intrauterine adhesions (IUA), particularly moderate to severe cases, is a leading cause of decreased menstrual flow and secondary infertility in women, affecting an estimated 2.8%∼46% of infertile women. Hysteroscopy remains the…

LPM7100328 is a novel oral GnRH antagonist being developed for the prevention of premature luteinizing hormone (LH) surges in women undergoing controlled ovarian stimulation. The studies presented herein reported assessment of safety in fav…

BackgroundRed blood cell volume distribution width (RDW) and albumin have been increasingly recognized for their roles in inflammatory diseases. However, the relationship between RDW-to-albumin ratio (RAR) and acute kidney injury (AKI) in a…

OBJECTIVE: To investigate the differences in pregnancy outcomes between fresh embryo transfer (ET) and frozen embryo transfer (FET) in women of advanced age undergoing assisted reproductive technology (ART), and to provide evidence for opti…

OBJECTIVE: The aim of the present study was to analyze pregnancy outcomes among patients diagnosed with first-trimester decidual polyps (DPs) following fresh embryo transfer who underwent expectant management and to further explore risk fac…