A Izu

No ORCID on file · 2 papers in corpus

nonrandomized-trial 1979

Anaprox in dysmenorrhea: reduction of pain and intrauterine pressure

American journal of obstetrics and gynecology ·doi:10.1016/0002-9378(79)90430-7

In a double-blind parallel trial, 24 dysmenorrheic women received a single dose of Anaprox (1,100 mg) or placebo. Over the next 2 hours, pain intensity was scored and intrauterine pressure was measured using an immobilized microballoon. At …

nonrandomized-trial 1979

Naproxen and naproxen sodium in dysmenorrhea: development from in vitro inhibition of prostaglandin synthesis to suppression of uterine contractions in women and demonstration of clinical efficacy

Acta obstetricia et gynecologica Scandinavica. Supplement ·doi:10.3109/00016347909157802

Abstract. “In vitro” experimentation has shown that naproxen inhibits prostaglandin synthetase generated by uterine microsomes of pregnant rats. In another in vitro system, naproxen inhibited electrically induced contractions of an isolated…