Sayeh Saravi

No ORCID on file · 2 papers in corpus

article 2026

Integrative mRNA and miRNA Profiling Identifies Shared and Subtype-Associated PI3K–AKT–mTOR Pathway Dysregulation and Candidate miRNA-Mediated Regulatory Interactions in Endometriosis-Associated Ovarian Cancers (EAOCs)

·doi:10.3390/biomedicines14091991

Background: Endometriosis-associated ovarian cancers (EAOCs), including ovarian clear cell (OCCC) and endometrioid ovarian carcinoma (EnOC) subtypes, frequently exhibit transcriptomic dysregulation of the PI3K/AKT/mTOR signalling axis. Whil…

preprint 2026

MicroRNA-Mediated Rewiring of the PI3K–AKT–mTOR Axis Reveals Divergent Regulatory Networks and Metabolic Vulnerabilities in Endometriosis-Associated Ovarian Cancers (EAOCs)

·doi:10.20944/preprints202607.1410.v1

Background: Endometriosis-associated ovarian cancers (EAOCs), including clear cell (OCCC) and endometrioid (EnOC) subtypes, frequently activate the PI3K/AKT/mTOR signaling axis. While genomic aberrations are well documented, the coordinate…