Montserrat García-Closas

No ORCID on file · 4 papers in corpus
observational 2024
Germline copy number variants and endometrial cancer risk
Human genetics ·doi:10.1007/s00439-024-02707-9

Known risk loci for endometrial cancer explain approximately one third of familial endometrial cancer. However, the association of germline copy number variants (CNVs) with endometrial cancer risk remains relatively unknown. We conducted a …

observational 2018
Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study
The journal of pathology. Clinical research ·doi:10.1002/cjp2.109

We aimed to validate the prognostic association of p16 expression in ovarian high-grade serous carcinomas (HGSC) and to explore it in other ovarian carcinoma histotypes. p16 protein expression was assessed by clinical-grade immunohistochemi…

other 2018
Identification of nine new susceptibility loci for endometrial cancer
Nature communications ·doi:10.1038/s41467-018-05427-7

Endometrial cancer is the most commonly diagnosed cancer of the female reproductive tract in developed countries. Through genome-wide association studies (GWAS), we have previously identified eight risk loci for endometrial cancer. Here, we…

review 2016
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer
Gynecologic Oncology ·doi:10.1016/j.ygyno.2015.04.034

OBJECTIVE: Clinical genetic testing is commercially available for rs61764370, an inherited variant residing in a KRAS 3' UTR microRNA binding site, based on suggested associations with increased ovarian and breast cancer risk as well as wit…