Renate Schön — Endo Lab

article 2009

Studies on the Biotransformation of the Progestagen Dienogest in the Rabbit *)

·doi:10.1055/s-0029-1210898

Following administration of 14 alpha, 15 alpha-3H-Dienogest (STS 557, 17 alpha-cyanomethyl-17 beta-hydroxy-4, 9-estradien-3-one) to female rabbits, extracts from urine, bile and plasma were separated by means of HPLC. Urinary and biliary me…

article 1998

Studies on the hydrogenation of the progestagen dienogest in vivo and in vitro in the female rabbit

·doi:10.1016/s0039-128x(98)00014-2

The biotransformation of the progestagen dienogest (17 alpha-cyanomethyl-17 beta-hydroxy-4,9-estradien-3-one) was studied in vivo in female rabbits and in vitro by liver homogenates from female rabbits and rats. In vivo, in the female rabbi…

article 1998

Studies on the hydrogenation of the progestagen dienogest in vivo and in vitro in the female rabbit - Different plasma levels following ingestion of DHEA-supplemented food and different metabolite patterns in plasma, bile, and urine