Rachael Natrajan

No ORCID on file · 2 papers in corpus · active 2021-2022

Study types

  • letter 1
  • other 1

Condition tags

  • endometriosis 2
letter 2022
Definitive study shows no association between ARID1A mutation status and clinical outcome in endometriosis-related ovarian cancers‡
The Journal of Pathology ·doi:10.1002/path.5973

The ARID1A tumour suppressor protein is a component of the SWI/SNF chromatin remodelling complex, which is mutated in approximately 20% of all human cancers. ARID1A mutational status is considered to hold prognostic significance in a range …

other 2021
ATARI trial: ATR inhibitor in combination with olaparib in gynecological cancers with ARID1A loss or no loss (ENGOT/GYN1/NCRI)
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1136/ijgc-2021-002973

BACKGROUND: ARID1A (AT-rich interactive domain containing protein 1A) loss-of-function mutations have been reported in gynecological cancers, including rarer subtypes such as clear cell carcinoma. Preclinical studies indicate that ARID1A mu…