Clusters of epithelial cells of the fallopian tube exhibiting aberrant p53 expression, termed "p53 signatures," are detected at a relatively high frequency and have been regarded as putative precursors of high-grade serous carcinoma (HGSC).…
The fallopian tube has emerged as a central organ in the pathogenesis of ovarian cancer, particularly high-grade serous carcinoma (HGSC). Detailed histopathological and molecular analyses have revealed a diverse spectrum of tubal epithelial…
Adenomyoma of the uterus is a biphasic nodular lesion composed of a mesenchymal component with smooth muscle differentiation and a glandular epithelium. The neoplastic nature of uterine adenomyomas has been controversial because some are co…
IntroductionWe have reported previously that fecal DNA testing of TWIST1 methylation in combination with the fecal immunochemical test for hemoglobin (FIT) (combination test) is useful for colorectal neoplasia screening. In this study, usin…
BackgroundLactobacillus gasseri OLL2809 can highly induce interleukin (IL)-12 production in immune cells. Even though beneficial properties of this strain for both humans and animals have been reported, the mechanism by which the bacteria i…
BackgroundThe Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable compariso…