Adenomyosis is a benign invasion of endometrial glands and stroma into the uterine myometrium. [1, 2]. It can present with heavy and painful menstrual bleeding or be asymptomatic [2-4]. Over last three decades the diagnosis of adenomyosis h…
ObjectiveTo investigate biomarkers and clinical parameters to distinguish ovarian cancers from benign ovarian tumours.MethodsSerum biomarkers (CA 125, human epididymis protein 4 [HE 4], interleukin-18 [IL-18], leptin, macrophage migration i…
Progesterone receptor modulators (PRM) are hormonally active drugs effective in the management of endometriosis and uterine leiomyomata. The endometrial effects of progestin blockade by PRMs in premenopausal women are currently being evalua…
Adenomyosis is defined by the presence of endometrial mucosa within the myometrium. This probably occurs by invagination of the basalis endometrium into the myometrium. The process of invagination and intramyometrial spreading may be facili…
ObjectivesTo review the morphological and molecular events responsible for uterine bleeding in health and disease.MethodsReview of pertinent literature focusing on the histology and pathophysiology of normal and abnormal uterine bleeding (A…
Adenomyosis refers to endometrial glands and stroma located haphazardly deep within the myometrium. Similar histological alterations may be found in extrauterine locations such as the rectovaginal septum. The aetiology and pathogenic mechan…
Perineal endometriosis was found unexpectedly in a 32-year-old woman with primary infertility. Since there had been no prior perineal trauma, the transport of endometrium through a venous or lymphatic route could have accounted for the loca…
Seventy nonpregnant women with extensive condylomata of the vagina were treated either with intravaginal 5-fluorouracil (5-FU) cream or the CO2 laser. Treatment results were correlated with the morphologic type of condylomata, ie, papillary…
The kinetic and fine structural characteristics and site of origin of the resurfacing uterine lining, as well as the influence of ovarian hormonal stimuli on the reparative processes of experimentally injured endometrium in the rabbit, were…
Stereoscopic morphologic studies on regenerating cyclic endometrium indicate that endometrial repair lasts 48 hours, beginning between cycle Days 2 to 3 and ending between cycle Days 4 to 5. During this period, endometrial repair is focused…
The morphologic observations made in this study indicate that postmenstrual endometrial resurfacing occurs by proliferation of epithelial cells originating from the stumps of residual basal glands and uterine surface lining, bordering the d…
A case of clear cell adenocarcinoma of endometrium was studied by means of light and electron microscopy, and was compared with gestational Arias-Stella cells, as well as with progestin-treated hyperplastic endometrium. The clear appearance…