Heather C. Whalley

ORCID: 0000-0002-4505-8869 · 4 papers in corpus
other 2025
Statistical learning to identify and characterise neurodevelopmental outcomes at 2 years in babies born preterm: model development and validation using population-level data from England and Wales
EBioMedicine ·doi:10.1016/j.ebiom.2025.105811

BACKGROUND: Children born preterm face elevated risks of neurodevelopmental impairments across domains. Prior studies have relied on expert-imposed typologies within single domains. This study applies statistical learning to a national data…

other 2024
Genome-wide association reveals a locus in neuregulin 3 associated with gabapentin efficacy in women with chronic pelvic pain
iScience ·doi:10.1016/j.isci.2024.110370

Chronic pelvic pain (CPP) in women with no obvious pelvic pathology has few evidence-based treatment options. Our recent multicenter randomized controlled trial (GaPP2) in women with CPP and no obvious pelvic pathology showed that gabapenti…

2023
Epigenetic scores indicate differences in the proteome of preterm infants
·doi:10.1101/2023.12.19.23300227

Background Epigenetic scores (EpiScores), reflecting DNA methylation (DNAm)-based surrogates for complex traits, have been developed for multiple circulating proteins. EpiScores for pro-inflammatory proteins, such as C-reactive protein (DNA…

article 2019
The use of brain functional magnetic resonance imaging to determine the mechanism of action of gabapentin in managing chronic pelvic pain in women: a pilot study
BMJ open ·doi:10.1136/bmjopen-2018-026152

OBJECTIVE: To inform feasibility and design of a future randomised controlled trial (RCT) using brain functional MRI (fMRI) to determine the mechanism of action of gabapentin in managing chronic pelvic pain (CPP) in women. DESIGN: Mechanist…