Simonetta Astigiano

ORCID: 0000-0002-8200-0666 · 3 papers in corpus
preprint 2018
Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain
·doi:10.1101/251397

Capsule Comparative analysis of gene expression signatures from endometriosis and mouse models shows that CACNAα2δs calcium-channel components involved in nociception are targets for the treatment of endometriosis-associated pain. Context D…

article 2018
Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain
Journal of pain research ·doi:10.2147/jpr.s163611

Background: It has been repetitively shown that the transcription factors DLX5 and DLX6 are drastically downregulated in endometriotic lesions when compared with eutopic endometrium. These findings suggest that regulatory cascades involving…

2011
TAp73 is downregulated in oocytes from women of advanced reproductive age.
Cell cycle (Georgetown, Tex.) ·doi:10.4161/cc.10.19.17585

Studies on oocyte transcriptome are important to understand the biological pathways involved in oogenesis, totipotence and early embryonic development. Moreover, genes regulating physiological pathways in gametes could represent potential c…