Samuel W. Lukowski

ORCID: 0000-0002-8598-7902 · 7 papers in corpus
other 2022
Communications biology ·doi:10.1038/s42003-022-03541-3

Cellular development is tightly regulated as mature cells with aberrant functions may initiate pathogenic processes. The endometrium is a highly regenerative tissue, shedding and regenerating each month. Endometrial stromal fibroblasts are …

2021
·doi:10.21203/rs.3.rs-596345/v1

Abstract Cellular development is tightly regulated as mature cells with aberrant functions may initiate pathogenic processes. The endometrium is a highly regenerative tissue, shedding and regenerating each month. Endometrial stromal fibrob…

observational 2019
Clinical epigenetics ·doi:10.1186/s13148-019-0648-7

BACKGROUND: Major challenges in understanding the functional consequences of genetic risk factors for human disease are which tissues and cell types are affected and the limited availability of suitable tissue. The aim of this study was to …

2019
other 2019
Human Reproduction ·doi:10.1093/humrep/dez279

STUDY QUESTION: Are genetic effects on endometrial gene expression tissue specific and/or associated with reproductive traits and diseases? SUMMARY ANSWER: Analyses of RNA-sequence data and individual genotype data from the endometrium ide…

other 2018
Scientific reports ·doi:10.1038/s41598-018-29462-y

Gene expression varies markedly across the menstrual cycle and expression levels for many genes are under genetic control. We analyzed gene expression and mapped expression quantitative trait loci (eQTLs) in endometrial tissue samples from …

observational 2017
Human Reproduction ·doi:10.1093/humrep/dex006

STUDY QUESTION: Do genetic effects regulate gene expression in human endometrium? SUMMARY ANSWER: This study demonstrated strong genetic effects on endometrial gene expression and some evidence for genetic regulation of gene expression in …